FOXO1 and alveolar rhabdomyosarcoma: The majority of ARMS are characterized by the presence of translocations t (2;13)(q36; q14) or t (1;13)(p36;q14), which form a fusion gene between PAX3-FOXO1 or PAX7-FOXO1, respectively (previously named as PAX3-FKHR or PAX7-FKHR) [3, 4].