As shown in Table 1, stromal score (ref. low), Immune score (ref. low), pT stage (ref. T1-T2), pN stage (ref. N0), pM stage (ref. M0), AJCC stage (ref. I-II), ISUP grade (ref. 1-2), AGPAT9, AQP7, HMGCS2, KLF15, MLXIPL and PPARGC1A expression (ref. low) were demonstrated as independent prognostic indicators for ccRCC patients (p<0.05). The gene discussed is PPARGC1A; the disease is nonpapillary renal cell carcinoma.