Adding to the known transcription factors activated during infection, NF-κB, c-Fos, EGR1, c-Myc, STAT3/6, HIF1-α or NFAT4A, we can now include UHRF1, which emerges as an important epigenetic initiator regulating gene expression in T. gondii-infected cells along with NF-κB, p53, c-Myc STAT and HIF1-α [17]. The gene discussed is MYC; the disease is infection.