Because the addition of the FGFR1 inhibitor AZD4547 actually led to downregulation of the tumor suppressor miR-214-3p in H1581 and DMS114 cells, we hypothesized that the downregulation of miR-214-3p partially accounted for the modest efficacy of AZD4547. The gene discussed is FGFR1; the disease is neoplasm.