However, these results changed substantially with further adjustment for major cardiovascular risk factors, comorbidities, severity of CAD, medications and vitamin supplementation (Table 2 Model 2), age-corrected RTL (Table 2 Model 3), vitamin B6, folate, HCY, IL-6, hsCRP, albumin, GOT, GPT, GGT and total bilirubin (Table 2 Model 4). This evidence concerns the gene GPT and coronary artery disorder.