LGALS1 and glioblastoma: The results show that the expression of FAM289 increased 6.54 times in early-stage (I–II) GBM tissues (p < 0.05) and 9.48 times in advanced-stage (III–IV) GBM tissues (p < 0.05), and the expression trend of Galectin-1 was similar to that of FAM289 (Fig. 7Bb).