SATB2 and colorectal carcinoma: In addition, the enrichment of H3K4me3 in the SATB2 promoter region (C4, C7, C9 locus) was detected by ChIP-qPCR in 10 pairs of CRC and adjacent tissues, which was consistent with the ChIP-seq data, the enrichment of H3K4me3 in the SATB2 promoter region was significantly reduced in the CRC tissues (Fig. 5f, right panel).