In addition, SATB2 overexpression suppressed CXCL9 and CXCL10 expression in CRC cells and SATB2-AS1 knockdown partially alleviated the decrease of CXCL9 and CXCL10 expression caused by SATB2 (Fig. 4e, Additional file 3: Figure S4d). This evidence concerns the gene CXCL10 and colorectal carcinoma.