As shown in Table 1, SATB2-AS1 expression was correlated with tumor invasion depth (P <  0.001 in cohort 1, P = 0.017 in cohort 2), lymph node metastasis (P <  0.001 in cohort 1, P <  0.001 in cohort 2), distant metastasis (P = 0.002 in cohort 1, P <  0.001 in cohort 2) and TNM stage (P <  0.001 in cohort 1, P <  0.001 in cohort 2). This evidence concerns the gene SATB2 and metastatic malignant neoplasm in the lymph nodes.