(A) The amount of receptor for advanced glycation end products (RAGE) in thoracic aorta tissue is higher in the chronic kidney disease (CKD) group compared with that in the control, the CKD + ALT-711 (advanced glycation end products [AGEs] breaker), and the CKD + spironolactone (SPL) groups. The gene discussed is AGER; the disease is chronic kidney disease.