AFP and neoplasm: As summarized in Table 1, α7-nAChR expression was significantly highly positively correlated with the smoking status (p < 0.001), alcohol consumption (p = 0.03), liver cirrhosis (p = 0.001), tumor size (p < 0.001), tumor number (p = 0.01), vascular invasion (p < 0.001), tumor recurrence (p = 0.001), and pathological stage (p = 0.001), but not with age, gender, AFP, or the viral status.