We would like to stress the fact that monocytopenia observed in the EEHV-HD cases was not due to the homing of monocytes/macrophages in the spleen since the Iba-1 immunolabeling positive cells in the spleen was not differed between the EEHV-HD cases and the EEHV-negative controls. This evidence concerns the gene AIF1 and Decreased total monocyte count.