Outside of its role in bone homeostasis, Rgs12 has also been shown to hold diverse and significant roles in other clinical contexts including pathological cardiac hypertrophy (Huang et al., 2016), tumor suppression in African American prostate cancer (Wang et al., 2017), and psychostimulant-induced increases in dopamine levels in the brain (Gross et al., 2018). The gene discussed is RGS12; the disease is neoplasm.