Children who carry a germline PV in TP53 have an approximately 42% risk of developing a TP53‐related cancer before age 16 (Le Bihan, Moutou, Brugières, Feunteun, & Bonaïti‐Pellié, 1995), and adult men have an approximately 73% lifetime risk of cancer (Chompret et al., 2000). Here, TP53 is linked to cancer.