RT‐PCR (Figure 2D) and immunohistochemistry assay (Figure 2E‐G) showed that levels of TLR4 and ATG7 were significantly increased in EG‐induced hyperoxaluria rat kidneys compared with controls, while miR‐20b‐3p‐enriched exosome treatment reversed this increase. This evidence concerns the gene TLR4 and Hyperoxaluria.