MiR‐181a‐2‐3p has been associated with cerebral cavernous malformations56 and follicular variant of papillary thyroid carcinoma (FVPTC).57 Another study showed that rs174545 (FADS1: miR‐181a‐2), affecting a microRNA‐binding site, can affect microRNA‐mediated regulation of cardiometabolic genes.58 Our results showed that miR‐181a‐2‐3p was significantly downregulated in CAD patients. Here, FADS1 is linked to follicular variant thyroid gland papillary carcinoma.