MiR‐181a‐2‐3p has been associated with cerebral cavernous malformations56 and follicular variant of papillary thyroid carcinoma (FVPTC).57 Another study showed that rs174545 (FADS1: miR‐181a‐2), affecting a microRNA‐binding site, can affect microRNA‐mediated regulation of cardiometabolic genes.58 Our results showed that miR‐181a‐2‐3p was significantly downregulated in CAD patients. Here, FADS1 is linked to differentiated thyroid carcinoma.