This has been associated with an acute long-term fear of developing secondary cancer and recurrence or metastasis of the original breast cancer (Wan et al., 2016; Ziner et al., 2012), as women diagnosed at a younger age often have more aggressive forms of cancer including invasive histopathology, greater node involvement, high grade, larger tumour size, increased human epidermal growth receptor 2 (HER2) and negative oestrogen receptors (Copson et al., 2013; Gajdos et al., 2000; Kheirelseid et al., 2011; Yazdani-Charati et al., 2019). The gene discussed is ERBB2; the disease is cancer.