ENO2 and neoplasm: Same experiments performed using BE(2)-C xenograft tumors, tumor suppression of α-N-catenin was not significant (Figure 4E, tumor volume, left; tumor mass, right), even though increased α-N-catenin was detected in tumor tissue with overexpressed CTNNA2, and no difference on NSE expression between control and CTNNA2 tumor tissues (Figure 4F).