The activation of NF-κB induces the expression of multiple molecules, including cyclooxygenase-2, matrix metallopeptidase-9 and adhesion molecule intracellular adhesion molecule 1, vascular cell adhesion molecule 1 and endothelial-leukocyte adhesion molecule 1, all of which are linked to cancer cell invasion and metastasis [30]. The gene discussed is PTGS2; the disease is cancer.