FCER2 and B-cell chronic lymphocytic leukemia: Chronic lymphocytic leukemia is a significant sub group of chronic leukemias in adults.1 Chronic lymphocytic leukemia patients present with lymphadenopathy and peripheral blood lymphocytosis > 5 x 109/L which is characterized by CD 5+, CD19+ and CD23+ on immunophenotyping.2 These lymphocytes are morphologically mature but functionally incompetent.