To further evaluate CDK5 phosphorylation of TRIM59 at S308 (p-TRIM59S308), we generated a rabbit polyclonal antibody that specifically recognized p-TRIM59S308 through a commercial vendor and validated its specificity for p-TRIM59S308 in LN229/EGFRvIII GBM cells and a clinical GBM specimen (Supplementary Fig. 5b and 5c). This evidence concerns the gene CDK5 and glioblastoma.