EWSR1 and sarcoma: Given that EWS/ATF1 affects gene expression via binding to cyclic AMP response element (CRE) of the genome using the DNA-binding domain of ATF18, we compared the distribution of EWS/ATF1 binding in sarcoma cells (G1297) and sarcoma-iPSC MEFs at 12 h after Dox treatment by chromatin immunoprecipitation-sequencing (ChIP-Seq) analysis.