Furthermore, MAZ-overexpressing PC-3 cells exhibited more metastatic foci and severe osteolytic areas of metastatic tumors, as well as a shorter survival and bone metastasis-free survival compared with the vector group; conversely, the mouse group injected with the MAZ-silenced PC-3 cells yielded the opposite results (Fig.3d-g). Here, MAZ is linked to metastatic neoplasm.