Furthermore, Okugawa and co-workers, in a cohort of 308 patients with operable CRC, reported that low SMI (using sex-specific median values of psoas muscle index, male: 286.8 mm2/m2, female: 210.6 mm2/m2) was significantly associated with elevated CRP and low albumin [45]. The gene discussed is ALB; the disease is colorectal carcinoma.