NF1 and coronary artery disorder: To further evaluate the type and prevalence of CHD in NF1 and better define the clinical and molecular characteristics of NF1 patients with CHD, we retrospectively revised the prevalence and type of cardiac and non-cardiac features, as well the mutation spectrum, in a large series of patients with molecularly confirmed NF1, and correlated the mutation type with the presence and subgroups of CHD.