NOL4L (nucleolar protein 4 like) is also known as C20orf112. This gene is reported to be one of the fusion partners of RUNX1 (runt-related transcription factor 1) in acute myeloid leukemia and of PAX5 (paired box 5) in acute lymphoblastic leukemia; however, its precise role is still to be clarified [47,48]. This evidence concerns the gene PAX5 and acute lymphoblastic leukemia.