In our previous studies, we have extensively reported on the anticancer properties of resveratrol (trans-3,5,4′-trihydroxystilbene, Res) and its natural analogs, specifically pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene, Pter), through their potent targeting of MTA1-associated tumor promoting signaling in PCa in vitro and in vivo [12,28,29,30]. The gene discussed is MTA1; the disease is posterior cortical atrophy.