ABCA1 and Stroke: In addition, data from hematological parameters showed that when compared to WT and LDLR+/– hamsters, LDLR–/– hamsters had a higher RBC and LYM count; however, ABCA1–/– hamsters exhibited a higher WBC and LYM count, but lower numbers of PLT and reduced MPV and PDW, suggesting that changes of cholesterol metabolism diversely affected hematologic parameters, which may contribute to systemic inflammation and could potentially have predictive value for stroke severity (Table 1).