Among these genes, MYH10, ACTC1, FLNC and TPM2 exhibited the lower expression in the atherosclerosis samples, while the expressions of CXCL2, ITGAX, SELL, CCR2, LCP2, FPR2, NLRP3, IL1B, and CXCL8 were up-regulated in the atherosclerosis samples, suggesting that they may exert pivotal functions in the occurrence or progression of atherosclerosis. The gene discussed is CCR2; the disease is atherosclerosis.