Notably, several stimuli couple increased FGF23 transcription with increased post-translational cleavage, including inflammation [12], iron deficiency [12, 43–45], erythropoietin [46–51], and parathyroid hormone [52], resulting in elevated concentrations of circulating total FGF23 but not intact FGF23. The gene discussed is FGF23; the disease is nutritional disorder.