Highly purified and concentrated AAV vectors, 2 × 109 genomic particles (gp) coding for human pDyn (AAV‐pDyn), or non‐functional control vectors (AAV‐ΔGFP) were injected into the epileptogenic focus about 1 month after KA injection, when focal epilepsy had developed. The gene discussed is PDYN; the disease is focal epilepsy.