Genome‐wide association studies also identify several HDL cholesterol genes associated with AMD susceptibility, including genes encoding ATP‐binding cassette transporter A1 (ABCA1), cholesteryl ester transfer protein (CETP), apolipoprotein E (APOE), hepatic lipase C (LIPC), and lipoprotein lipase precursor (LPL) (Chen et al, 2010; Neale et al, 2010; Fritsche et al, 2013, 2016). The gene discussed is APOE; the disease is age-related macular degeneration.