FOXG1 and chronic kidney disease: Thus in our study, we also used Sox2CreER/+ mice as the control to avoid overestimating the effect of cKD of Foxg1. The statistical analysis showed that although Sox2CreER/+ mice also had some extra IHCs, Sox2CreER/+ Foxg1loxp/loxp mice had significantly more extra HCs than Sox2CreER/+ mice (Fig. 1e–g).