Bone scintigraphy or 18F‐NaF PET/CT also assists in exclusion of osteopoikilosis from the differential diagnosis and in detection of distant sites of melorheostosis.17, 18, 19 Classic candle‐wax appearance with exuberant growth of cortical bone seen on radiographs has been shown to be predictive of MAP2K1‐positive melorheostosis.9 Here, MAP2K1 is linked to osteopoikilosis.