At the multivariate analysis of independent predictors found at univariate analysis, positive PCT+ [OR 4.1 (CI 95% 2.2-8.3), p < 0.0001] and heart failure [1.8 (CI 95%1.05-5.5), p = 0.003] were independent predictors of in-hospital mortality. The gene discussed is CALCA; the disease is heart failure.