After the discussion in the last few paragraphs, in OSCC, the expression of TGFB1 and SPP1 were different and the expression of other subclinical sites of HNSCC was not reported.LAMB3 was upregulated in HNSCC patients but there is no specific head and neck subsites in the report. This evidence concerns the gene LAMB3 and head and neck squamous cell carcinoma.