A decline in this population was associated with faster disease progression, while no decline was observed in individuals with controlled infection.98 Administration of zoledronic acid with IL‐2 in HIV‐infected, antiretroviral naïve patients was associated with Vδ2+ T‐cell expansion, dendritic cell activation and increased HIV‐specific CD8+ T‐cell responses.99 It was also recently shown that γδ T cells can be isolated from antiretroviral suppressed, HIV‐infected individuals and that these cells can kill autologous HIV‐infected CD4+ T cells. Here, CD8A is linked to infection.