The difference of genotype frequencies among hypertension and normal groups were statistically significantat loci rs4425 (A/T) and rs4337 (G/C) in the ACE gene, at locus rs129876 (G/A) in the ATR gene and at locus rs1912 (C/T) in the CYP11B2 gene. The gene discussed is ACE; the disease is Hypertension.