KIT and acute myeloid leukemia: To investigate the sub-cellular localization of endogenous KIT, we performed confocal immunofluorescence microscopic analyses in pt18 (mouse mast cell line, KIT wild-type (WT)), Kasumi-1 (human AML, KITWT/N822K), SKNO-1 (human AML, KITN822K/N822K), and HMC-1.1 (human MCL, KITWT/V560G) (Fig. 1a).