LC3 levels were increased in Baf-1-treated cells compared to the 5-HT3RA-treated cells (Figure 4), demonstrating that 5-HT3RAs act as strong autophagy inducers and the growth inhibitory effects of 5-HT3RAs are associated with autophagy via ERK activation in lung cancer cells. This evidence concerns the gene MAP1LC3A and lung carcinoma.