FANCA and Fanconi anemia: In mammals, the main mechanism for ICL repair is the so-called Fanconi anemia (FA) pathway that involves 22 FANC (Fanconi anemia complementation group) genes (FANCA/ B/ C/ D1/ D2/ E/ F/ G/ I/ J/ L/ M/ N/ O/ P/ Q/ R/ S/ T/ U/ V and W) [115,116,117,118,119].