The variables considered were BW, GA, antenatal steroids, pH, pCO2, HCO3, base excess (BE), max C reactive protein levels from days 1 to 8, surfactant doses, severity of respiratory distress syndrome (RDS), delivery, premature pre-labor rupture of membranes (PPROM), pre-eclampsia, sex, medically-induced pregnancy, PDA, fetal growth restriction. The gene discussed is CRP; the disease is Patent ductus arteriosus.