CYP2E1 and Hypertension: To further comprehend the genetic alterations in prenatally DEX-exposed animals that could predispose them to hypertension and cardiovascular complications, we chose to analyze the expression of phenylalanine hydroxylase (PAH), a member of the solute carrier family of Na+/H exchangers SLC9A3, and the cytochrome P450 oxidases E class CYP2E1 genes (Fig 6) due to their role in catecholamine biosynthesis and regulation.