Further, in 10 of 11 cancers (except thyroid and skin) (Figure 4B; eFigure 11 in the Supplement), the abundance of TIL immune cell troops, such as NK, NK T cells, γδ T cells, CD103+ dendritic cells, activated CD8+ T cells, CD4+ T cells, and other immune cells, was negatively associated with the number of NK cell-defective genes (patients with HNSC: R = −0.21; 95% CI, −0.60-1.25; P = .07). The gene discussed is CD8A; the disease is cancer.