Similar as described for tumors in R172H‐mutant mice (Terzian et al, 2008), we noted varying levels of p53EE expression in spontaneous tumors arising in p53EE/EE or p53EE/− mice, with a high fraction (67%) of p53EE/EE tumors exhibiting p53EE stabilization comparable to p53‐mutated human cancer samples (Figs 6C and EV4 and EV5). Here, TP53 is linked to cancer.