This population has been enabling relevant clinical descriptions in DCM,as in the most recent studies addressing different genes (TTN,LMNA, FLNC, orBAG3).19-21 Cosegregationof variants in these genes has been demonstrated as disease-causing in multipleDCM-families, and the ever-increasing number of identified carriers has enabledgenotype-phenotype correlation analyses on the prognosis of thedisease.22,23. Here, TTN is linked to familial dilated cardiomyopathy.