Moreover, it has been proposed that TTNtvmay be acting as a susceptibility genetic substrate to different DCM-types(anthracycline-induced, peripartum, and alcoholic).27-29Finally, patients with titin cardiomyopathy appear to have a more favorableclinical course and respond better to drug therapy than those affected byvariants in the lamin (LMNA) gene.31-33. Here, TTN is linked to familial dilated cardiomyopathy.