In this sample, the incidence of cardiac events incarriers of BAG3 variants with DCM was 5.1% per year (outcomes:sustained ventricular tachycardia, sudden death, HF death, need for ventricularassist device and HTx), with a predominance of HF-events versus a lower numberof arrhythmic outcomes. Here, BAG3 is linked to familial dilated cardiomyopathy.