ANO2 and Anxiety: Given that anxiety and fear conditioning involves multiple brain regions including amygdala and hippocampus (Chen et al., 2016; Hall et al., 2001; Kochli et al., 2015; Vazdarjanova and McGaugh, 1999; Weeden et al., 2015; Xu et al., 2016; Yin et al., 2002), it is important to examine Ano2 expression and physiological function in amygdala to assess the potential relevance to anxiety.