Within the broader category of FA synthesis, one acyl-CoA carboxylase (ACC), one FA desaturase (delta 9), and two keto-acyl-CoA synthases (KCS1) were upregulated in PWS individuals (PWS2 and PWSA) compared with individuals from the GAK stations (GAK4, GAK9, and GAK14) (Fig. 7). This evidence concerns the gene GAK and Prader-Willi syndrome.