CD8A and neoplasm: Although the proportion of CD8+ T cells (Fig. 2f) or CD45RO+ cells (Supplementary Fig. 4o) as single markers did not predict distant relapse-free survival post-chemotherapy, elevated tumor percentages of CD45RO+ CD8+ T cells predicted favorable patient outcome and extended metastasis-free survival (Fig. 2g, representative images in 2d), suggesting that post-chemotherapeutic induction of memory T cells is imperative in preventing distant relapse.