Moreover, these studies identified three additional SNPs within intron 1 of the FTO gene that were associated with severe childhood and morbid adult obesity (rs1421085 and rs17817449) (4, 5), and with obesity-related traits (rs9930506) (45), thus yielding a population attributable risk of 22% for common obesity (55). The gene discussed is FTO; the disease is obesity due to melanocortin 4 receptor deficiency.