Adjuvant CHT was delivered in a different proportion of patients according to primary CRC TNM/UICC stage (p < 0.001) and previously resected extrathoracic metastasis (38/45 vs. 77/134, p < 0.001), while hilar nodal involvement (3/3 of N+ vs. 77/105 of N0), higher CEA (36/75 vs. 74/97), and short DFI (20/25 vs. 95/154) where not statistically associated to adjuvant CHT administration. Here, CEACAM5 is linked to colorectal carcinoma.