The presence of MOG Ab has been most commonly associated with monophasic and recurrent episodes of optic neuritis (ON), acute disseminated encephalomyelitis (ADEM), and transverse myelitis (TM) in children, as well as unilateral ON, bilateral ON, and TM in adults [5, 6, 13, 23, 28, 35, 39, 42, 47, 75]. The gene discussed is MOG; the disease is optic neuritis.