Other genes that were found to be mutated in at least 2 CTCs per patient were ARID1A, CDH1, and TTN. Genes that were mutated in 1 CTC in at least 2 patients were RYR2, LRP2, and PI3KCA. Although more cancer-related mutations were detected, we considered them as potentially false positive and therefore not report them. This evidence concerns the gene RYR2 and cancer.